Pathogenic significance of interleukin-6 (IL-6/BSF-2) in Castleman's disease

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Pathogenic significance of interleukin-6 (IL-6/BSF-2) in Castleman's disease.

Castleman's disease is a syndrome consisting of giant lymph node hyperplasia with plasma cell infiltration, fever, anemia, hypergammaglobulinemia, and an increase in the plasma level of acute phase proteins. It has been reported that clinical abnormalities disappear after the resection of the affected lymph nodes, suggesting that products of lymph nodes may cause such clinical abnormalities. In...

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ژورنال

عنوان ژورنال: Blood

سال: 1989

ISSN: 0006-4971,1528-0020

DOI: 10.1182/blood.v74.4.1360.bloodjournal7441360